Conformational studies on 2-methyl- and 2,NN-trimethyl-chroman-3-amine and derivatives

1 January 1973

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 2

No. 2,p. 227-232
https://doi.org/10.1039/p29730000227

Abstract

The synthesis of cis- and trans-2-methyl- and 2,NN-trimethylchroman-3-amines is described. Configurations and preferred conformations are assigned to the free bases, and to derivatives (hydrochlorides, N-acetyl, N-phthaloyl) by interpretation of proton magnetic resonance spectra recorded at 220 MHz.

Keywords

CONFORMATIONAL
TRIMETHYLCHROMAN
PREFERRED
RESONANCE
ACETYL
TRANS