APPLICATION OF LOD METHOD TO DETECTION OF LINKAGE BETWEEN A QUANTITATIVE TRAIT AND A QUALITATIVE MARKER - SIMULATION EXPERIMENT
- 1 January 1976
- journal article
- research article
- Vol. 28 (2) , 167-173
Abstract
Simulation experiments were performed to assess the power of the lod method for detecting linkage between a quantitative trait and a qualitative marker. Using family data on the Amy2 (amylase)-Duffy linkage, linkage detection is feasible in certain limited circumstances. The same qualitative data yielded no evidence for a significant difference in male and female recombination fractions.This publication has 16 references indexed in Scilit:
- Quantitative linkage: a statistical procedure for its detection and estimationAnnals of Human Genetics, 1975
- The prior probability of autosomal linkageAnnals of Human Genetics, 1975
- Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies.1974
- Comment on Dr. Robertson's communicationBehavior Genetics, 1974
- Studies on blood and urine glucose in Seminole Indians: indications for segregation of a major gene.1974
- The use of biochemical data in screening for mutant alleles and in genetic counselling*Annals of Human Genetics, 1974
- The Relation of Parental Sex and Age to Recombination in the HL-A SystemHuman Heredity, 1973
- Demonstration of a sex difference in recombination fraction in the loose linkage, Rh and PGM1Annals of Human Genetics, 1972
- The investigation of linkage between a quantitative trait and a marker locusBehavior Genetics, 1972
- THE MAPPING OF HUMAN CHROMOSOMESAnnual Review of Genetics, 1971