MALE-RESTRICTED EXPRESSION OF H-Y ANTIGEN ON PREIMPLANTATION MOUSE EMBRYOS
- 1 January 1984
- journal article
- research article
- Published by Wolters Kluwer Health in Transplantation
- Vol. 37 (1) , 7-8
- https://doi.org/10.1097/00007890-198401000-00004
Abstract
The H-Y (male) antigen is detectable on 50% of eightcell mouse embryos. We show that 82% of the offspring resulting from the transfer of (C57BL/6XA/J)F1 embryos surviving treatment with H-Y antibody and complement to the uteruses of pseudopregnant mice are female. The increased ratio of female-to-male births indicates that the H-Y-bearing embryos are male.Keywords
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