Homoconjugate addition of Grignard reagents to spiroactivated cyclopropanes. An approach to the total synthesis of (±)-brefeldin A
- 1 January 1978
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 17,p. 754-756
- https://doi.org/10.1039/c39780000754
Abstract
The homoconjugate addition of Grignard reagents to spiroactivated cyclopropanes has been used for the conversion of the readily available cyclopropane (6a) into the key intermediate (4) for the preparation of (±)-brefeldin A.Keywords
This publication has 2 references indexed in Scilit:
- Über die Isolierung neuer Stoffwechselprodukte aus Penicillium brefeldianum DODGEHelvetica Chimica Acta, 1963
- Decumbin, a New Compound from a Species of PenicilliumNature, 1958