Effect of dextranase on plaque formation and caries development in the rat
- 1 August 1978
- journal article
- research article
- Published by Wiley in European Journal of Oral Sciences
- Vol. 86 (4) , 231-236
- https://doi.org/10.1111/j.1600-0722.1978.tb00623.x
Abstract
Plaque formation and caries development were studied in 0-M rats fed Diet 2000 and infected with S. mutans 6715 and fecal flora from older caries-active rats. Merck dextranase, Beckman dextranase or Beckman glucanase 447 were administered singly or in combination to groups of 12 rats either as an addition to the diet or as a "mouthwash" twice daily, 5 per week. All enzymes studied were associated with significant inhibition of both plaque formation and caries development, especially on the buccal and lingual surfaces.Keywords
This publication has 15 references indexed in Scilit:
- Collaborative Evaluation of a Rat Caries Model in Six LaboratoriesJournal of Dental Research, 1977
- Enzymatic reduction of the colonization ofStreptococcus mutansin human dental plaqueActa Odontologica Scandinavica, 1973
- Caries and Plaque Inhibition by Mutanase in RatsCaries Research, 1972
- The effect of dextranase on caries activity in monkeys (Macaca irus)British Dental Journal, 1971
- Effect of dextranase on caries in rats harbouring an indigenous cariogenic bacterial floraArchives of Oral Biology, 1969
- The effects of a dextranase preparation on plaque and caries in hamsters, a preliminary reportThe Journal of the American Dental Association, 1968
- Enzymatic removal of artificial plaquesArchives of Oral Biology, 1968
- Periodontal lesions in the Syrian hamster—IIIArchives of Oral Biology, 1964
- Dental Caries in the Molar Teeth of RatsJournal of Dental Research, 1958
- Benign Hodgkin's disease (Hodgkin's paragranuloma)The Journal of Pathology and Bacteriology, 1952