Cytotoxicity of quinolones toward eukaryotic cells. Identification of topoisomerase II as the primary cellular target for the quinolone CP-115,953 in yeast.
Open Access
- 1 July 1992
- journal article
- abstracts
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 267 (19) , 13150-13153
- https://doi.org/10.1016/s0021-9258(18)42185-0
Abstract
No abstract availableKeywords
This publication has 30 references indexed in Scilit:
- Catalytic function of DNA topoisomerase IIBioEssays, 1991
- Effects of antineoplastic drugs on the post-strand-passage DNA cleavage/religation equilibrium of topoisomerase IIBiochemistry, 1991
- DNA Gyrase: Structure and FunctionCritical Reviews in Biochemistry and Molecular Biology, 1991
- Uncoupling the DNA cleavage and religation activities of topoisomerase II with a single-stranded nucleic acid substrate: evidence for an active enzyme-cleaved DNA intermediateBiochemistry, 1990
- Effect of antineoplastic agents on the DNA cleavage/religation reaction of eukaryotic topoisomerase II: inhibition of DNA religation by etoposideBiochemistry, 1989
- Purification and characterization of an altered topoisomerase II from a drug-resistant Chinese hamster ovary cell lineBiochemistry, 1989
- Biochemical basis for the interactions of type I and type II topoisomerases with DNAPharmacology & Therapeutics, 1989
- DNA TOPOISOMERASESAnnual Review of Biochemistry, 1985
- DNA topoisomerase II is required at the time of mitosis in yeastCell, 1985
- Yeast DNA topoisomerase II is encoded by a single-copy, essential geneCell, 1984