Epstein–Barr Virus in Action in Vivo
- 14 May 1998
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 338 (20) , 1461-1463
- https://doi.org/10.1056/nejm199805143382011
Abstract
Epstein–Barr virus (EBV), a B-lymphotropic herpesvirus carried by almost everyone as a lifelong asymptomatic infection, is implicated in the pathogenesis of at least three malignant disorders of B cells.1 One is Burkitt's lymphoma, which in its endemic form in equatorial Africa almost always contains the virus. A rare sporadic form of Burkitt's lymphoma that occurs in Western countries contains the virus in 10 to 20 percent of cases. The second B-cell tumor linked to EBV is classic Hodgkin's disease,2 which is associated with the virus in 40 percent of the cases in the West and in more than 80 percent . . .Keywords
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