TUMORS OF UPPER DIGESTIVE-TRACT OF ACI-N RATS GIVEN N-PROPYL-N-NITROSOURETHAN IN DRINKING-WATER

  • 1 January 1976
    • journal article
    • research article
    • Vol. 67  (4) , 549-+
Abstract
ACI/N rats of both sexes were given continuously 400, 200 or 100 ppm solutions of N-propyl-N-nitrosourethan (PNUE) as their drinking water. Papillomas and/or squamous cell carcinomas of the upper digestive tract were observed in 100% in all 3 groups. Morphogenesis of these tumors was also studied.

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