Synthesis and evaluation of unsymmetrical bis(arylcarboxamides) designed as topoisomerase-Targeted anticancer drugs
- 1 January 2002
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry
- Vol. 10 (1) , 19-29
- https://doi.org/10.1016/s0968-0896(01)00249-8
Abstract
No abstract availableKeywords
This publication has 28 references indexed in Scilit:
- Dicationic Bis(9-methylphenazine-1-carboxamides): Relationships between Biological Activity and Linker Chain Structure for a Series of Potent Topoisomerase Targeted Anticancer DrugsJournal of Medicinal Chemistry, 2001
- Bis(phenazine-1-carboxamides): Structure−Activity Relationships for a New Class of Dual Topoisomerase I/II-Directed Anticancer DrugsJournal of Medicinal Chemistry, 2000
- Structure−Activity Relationships for Substituted Bis(acridine-4-carboxamides): A New Class of Anticancer AgentsJournal of Medicinal Chemistry, 1999
- Phase I study of DMP 840 in pediatric patients with refractory solid tumorsInvestigational New Drugs, 1998
- Ultratight DNA Binding of a New Bisintercalating Anthracycline AntibioticBiochemistry, 1998
- A phase I and pharmacologic study of DMP 840 administered by 24-hour infusionAnnals of Oncology, 1998
- Chromophore-Modified Bis-Naphthalimides: Synthesis and Antitumor Activity of Bis-Dibenz[de,h]isoquinoline-1,3-dionesJournal of Medicinal Chemistry, 1997
- Structure-Based Design of a New Bisintercalating Anthracycline AntibioticJournal of Medicinal Chemistry, 1997
- Bisimidazoacridones and Related Compounds: New Antineoplastic Agents with High Selectivity against Colon TumorsJournal of Medicinal Chemistry, 1995
- Evaluation of a novel bis-naphthalimide anticancer agent, DMP 840, against human xenografts derived from adult, juvenile, and pediatric cancersCancer Chemotherapy and Pharmacology, 1994