Porous-layer open-tubular gas chromatography in combination with an ion trap detector to assess volatile metabolites in human breath

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Abstract
A method is described for the quantification of major volatile substances in human breath without preconcentration. Methanol, ethanol, acetaldehyde and acetone are well separated by porous-layer open-tubular column gas chromatography. Low-level detection was possible by means of an ion trap detector. Halothane has been used as internal standard.

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