Detection of UV purine photoproducts in a defined sequence of human DNA.
Open Access
- 1 February 1986
- journal article
- research article
- Published by Taylor & Francis in Molecular and Cellular Biology
- Vol. 6 (2) , 707-709
- https://doi.org/10.1128/mcb.6.2.707
Abstract
The UV-irradiated, 3'-end-labeled, 92-base-pair terminus of the human alphoid sequence was incubated with purified endonuclease v. Previously unreported photoproducts were incised at purine loci. These were not pyrimidine photodimers, 6-4'-(pyrimidin-2'-one)-pyrimidines, base loss sites, or ring-opened purines. Therefore, purine-containing photoproducts, possibly dimers, were incised by the enzyme preparation.This publication has 19 references indexed in Scilit:
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