Determination of Terbutaline in Postmortem Human Tissues by Gas Chromatography-Mass Spectrometry
- 1 May 1978
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Analytical Toxicology
- Vol. 2 (3) , 86-88
- https://doi.org/10.1093/jat/2.3.86
Abstract
A method is described for the quantitative analysis of terbutaline in human tissues. Gas chromatography and chemical ionization mass fragmentography are used for selective and sensitive detection. A detection limit of 1.5 ng of the free drug per gram tissue is observed when 0.5 g of the dry tissue is used. No interference from the major metabolite, the sulphate conjugate of terbutaline, is found. Finally the method is applied to the postmortem tissues of two persons who used terbutaline frequently.This publication has 1 reference indexed in Scilit:
- Quantitative analysis of terbutaline in serum and urine at therapeutic levels using gas chromatography—mass spectrometryJournal of Chromatography B: Biomedical Sciences and Applications, 1977