SOME EFFECTS OF A MONOAMINE OXIDASE INHIBITOR UPON CHANGES PRODUCED BY CENTRALLY ADMINISTERED AMINES
Open Access
- 1 October 1961
- journal article
- research article
- Published by Wiley in British Journal of Pharmacology and Chemotherapy
- Vol. 17 (2) , 261-266
- https://doi.org/10.1111/j.1476-5381.1961.tb01286.x
Abstract
In cats treated with subcutaneous or intraperitoneal injections of the monoamine oxidase inhibitor phenylisopropylhydrazine, the effects of 5-hydroxytryptamine injected into the lateral cerebral ventricle were greatly intensified and prolonged; the effects of adrenaline were potentiated to a lesser extent. Those of noradrenaline, dopamine and tryptamine were not intensified and were prolonged to only a slight degree.Keywords
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