Gangrene of the Female Breast with Anticoagulant Therapy: Report of Two Cases
- 1 May 1970
- journal article
- Published by Oxford University Press (OUP) in American Journal of Clinical Pathology
- Vol. 53 (5) , 622-626
- https://doi.org/10.1093/ajcp/53.5.622
Abstract
The characteristic clinical, gross, and microscopic findings of two cases of gangrene of the breast following Dicumarol therapy are presented. A comparison is drawn between this lesion and purpura fulminans, based on gross and microscopic appearance and on the theoretic relationship of each to the Sanarelli-Shwartzman phenomenon. It is suggested that a therapeutic trial with heparin, corticosteroids, dextran, and antibiotics is warranted prior to resorting to surgery.Keywords
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