Regional localization of a human cytochrome P-450 (CYP1) to chromosome 19q 13.1?13.3
- 1 July 1986
- journal article
- Published by Wiley in Annals of Human Genetics
- Vol. 50 (3) , 237-240
- https://doi.org/10.1111/j.1469-1809.1986.tb01044.x
Abstract
A phenobarbitone inducible cytochrome P-450 gene family (CYP1) has recently been localized to chromosome 19q13.1-qter. We have used a human liver cDNA probe in in situ hybridization experiments to metaphase chromosomes from two balanced translocation carriers, 46,XX,t(11;19) (q13;q13.1) and 46,XX,t(7;19) (q31.3;q13.3) to obtain a more precise localization. The results suggest a regional assignment for CYP1 to chromosome 19q13.1-13.3.Keywords
This publication has 2 references indexed in Scilit:
- A cytochrome P‐450 gene family mapped to human chromosome 19Annals of Human Genetics, 1985
- Isolation and sequence of a human cytochrome P-450 cDNA clone.Proceedings of the National Academy of Sciences, 1985