Properties of Genes Involved in the Control of Isocitrate Lyase Production in Aspergillus nidulans

Publisher Website
Google Scholar
Abstract
The interaction between genes of Aspergillus nidulans conferring constitutive synthesis of isocitrate lyase (iclc A and iclcB) and fluoroacetate resistance (facB) has been investigated. Although facB mutants are unable to induce the glyoxylate cycle enzyme isocitrate lyase in response to acetate as sole carbon source, this phenotype was suppressed in recombinants of the type iclc;facB. The iclcA and iclcB mutations do not alter significantly the activities of eight enzymes of intermediary metabolism assayed. We conclude that the iclc genes are probably bona fide isocitrate lyase regulatory genes.

This publication has 0 references indexed in Scilit: