Locked-in syndrome
Top Cited Papers
- 17 February 2005
- Vol. 330 (7488) , 406-409
- https://doi.org/10.1136/bmj.330.7488.406
Abstract
Introduction The locked-in syndrome is caused by an insult to the ventral pons, most commonly an infarct, haemorrhage, or trauma. The characteristics of the syndrome are quadriplegia and anarthria with preservation of consciousness. Patients retain vertical eye movement, facilitating non-verbal communication. Ten year survival rates as high as 80% have been reported. Even limited physical recovery can improve quality of life and enable patients to return to live with their families. Early referral to a specialist rehabilitation service for specialist care and technology is therefore important.Keywords
This publication has 16 references indexed in Scilit:
- Impairment, Activity, Participation, Life Satisfaction, and Survival in Persons With Locked-In Syndrome for Over a DecadeJournal of Head Trauma Rehabilitation, 2003
- Locked-in syndrome: improvement in the prognosis after an early intensive multidisciplinary rehabilitation11No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the author(s) or upon any organization with which the author(s) is/are associated.Archives of Physical Medicine and Rehabilitation, 2003
- Cognitive dysfunction after isolated brain stem insult. An underdiagnosed cause of long term morbidityJournal of Neurology, Neurosurgery & Psychiatry, 2002
- Survey: The locked-in syndrome: a syndrome looking for a therapyBrain Injury, 2002
- Functional outcome in brain stem stroke patients after rehabilitationArchives of Physical Medicine and Rehabilitation, 1996
- Persistence of distal motor control in the locked in syndrome. Review of 11 patientsSpinal Cord, 1995
- Life-sustaining treatment and locked-in syndromeThe Lancet, 1993
- Locked-in syndrome: a review of 139 cases.Stroke, 1986
- Locked‐in syndrome with recoveryAnnals of Neurology, 1980
- Varieties of the locked-in syndromeZeitschrift für Neurologie, 1979