Vanadium: A Modifier of Drug-Metabolizing Enzyme Patterns and Its Critical Role in Cellular Proliferation in Transplantable Murine Lymphoma

Publisher Website
Google Scholar
Abstract
Vanadium, as ammonium monovanadate, has been found to stimulate tumour cell proliferation in mice bearing a transplantable ascitic lymphoma. Markers including microsomal cytochrome P-450, UDP-glucuronyltransferase and cytosolic glutathione-S-transferase showed substantial alterations in a dose-responsive manner with vanadium administration when compared to the controls. Stimulation of tumour progression is also reflected by increased tumour cell count and decreased survival of the host.

This publication has 0 references indexed in Scilit: