Effect of Dopamine in Stress Ulcer of Rats

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Abstract
Dopamine''s effect in stress-induced ulceration of stomach mucosa employing a hypoxia-immobilization stress was investigated in rats. Administration (i.v.) of small doses of dopamine (3 .mu.g/kg body wt per min) significantly lowered development of mucosa erosions. A bilious reflux which was observed after dopamine infusion but not in controls may be considered a side effect of this agent.