THE EFFECTS OF EATING AND OF SHAM FEEDING UPON THE ABSORPTION OF VITAMIN A PALMITATE IN MAN 1
Open Access
- 1 July 1954
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 33 (7) , 1015-1021
- https://doi.org/10.1172/jci102968
Abstract
Serum vit. A levels were detd. in normal adults who received a test dose of 100,000 u[mu] synthetic vit. A palmitate in corn oil. Falsely flat tolerance curves were obtained in 5 of 16 subjects studied for 8 hrs. when fasting. These subjects showed normal @@@ absorptive curves when a meal was fed 2 hrs. after admn. of the test dose. Sham feeding at 2 hrs. also produced normal curves. Three totally-gastrectomized subjects showed the same normal response to eating. Eating accelerated the rise in serum vit. A when the test dose was administered intraduodenally; atropine intramusc. slowed the rate but not the max. serum concn. attained. Exclusion of pancreatic and biliary secretions from upper jejunum did not prevent response to eating when test dose was administered via tube into this loop.Keywords
This publication has 6 references indexed in Scilit:
- Comparative Metabolic Effects of Ingestion of Water or 1 Per Cent Sodium Chloride Solution in the Rat With a Thoracic Duct Lymph FistulaAmerican Journal of Physiology-Legacy Content, 1952
- GASTROINTESTINAL HORMONESPhysiological Reviews, 1950
- THE DETERMINATION OF VITAMIN A AND CAROTENE IN SMALL QUANTITIES OF BLOOD SERUMJournal of Biological Chemistry, 1946
- THE EFFECT OF ATROPINE UPON THE ABSORPTION OF VITAMIN AJournal of Clinical Investigation, 1943
- THE PLASMA LEVELS OF VITAMIN A AFTER THE INGESTION OF STANDARD DOSES: STUDIES IN NORMAL SUBJECTS AND PATIENTS WITH CIRRHOSIS OF THE LIVER 1Journal of Clinical Investigation, 1941
- Intestinal Absorption of Vitamin A in the Normal RatJournal of Nutrition, 1940