Dopamine-4-O-sulfate: a possible precursor of free norepinephrine
- 1 September 1979
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Biochemistry
- Vol. 57 (9) , 1159-1162
- https://doi.org/10.1139/o79-149
Abstract
Incubation of dopamine-4-O-sulfate with purified bovine dopamine-.beta.-hydroxylase led to the formation of free norepinephrine [NE]. The production of free NE was completely inhibited in the presence of 5.6 mM of fusaric acid, an inhibitor of dopamine-.beta.-hydroxylase. No sulfatase activity was detected in the incubation medium. The reaction of dopamine-4-O-sulfate with dopamine-.beta.-hydroxylase had an apparent Km of 2.6 mM.This publication has 0 references indexed in Scilit: