HEREDITARY COMPLEMENT (C2) DEFICIENCY WITH DISCOID LUPUS ERYTHEMATOSUS AND IDIOPATHIC ATROPHODERMA

Abstract
A Family with hereditary deficiency of the second component of complement was studied. Three siblings were homozygous for C2 deficiency and two of them had associated skin diseases. Ono sister presented with idiopathic atrophoderma and the other had clinical and pathological manifestations of discoid lupus erythematosus. This is the first description of an association between idiopathic atrophoderma and C2 deficient state.

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