CYP2D6.10 present in human liver microsomes shows low catalytic activity and thermal stability

This publication has 12 references indexed in Scilit:

• Analysis of the gene in relation to dextromethorphan -demethylation capacity in a Japanese population
  Clinical Pharmacology & Therapeutics, 1999
• Establishment of a Novel Host, High-Red Yeast That Stably Expresses Hamster NADPH–Cytochrome P450 Oxidoreductase: Usefulness for Examination of the Function of Mammalian Cytochrome P450
  Archives of Biochemistry and Biophysics, 1997
• Different Structural Requirements at Specific Proline Residue Positions in the Conserved Proline-rich Region of Cytochrome P450 2C2
  Journal of Biological Chemistry, 1996
• P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature
  Pharmacogenetics, 1996
• Malfolded Cytochrome P-450(M1) Localized in Unusual Membrane Structures of the Endoplasmic Reticulum in Cultured Animal Cells1
  The Journal of Biochemistry, 1995
• Importance of the Proline-Rich Region Following Signal-Anchor Sequence in the Formation of Correct Conformation of Microsomal Cytochrome P-450s1
  The Journal of Biochemistry, 1993
• Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes.
  Journal of Biological Chemistry, 1990
• Absence of hepatic cytochrome P450bufI causes genetically deficient debrisoquine oxidation in man
  Biochemistry, 1988
• High-performance liquid chromatographic assays for bufuralol 1′-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver
  Analytical Biochemistry, 1987
• Effects of lipid peroxidation on activities of drug-metabolizing enzymes in liver microsomes of rats
  Biochemical Pharmacology, 1973