Ocular Hypertension Following Intravenous Infusion of Prostaglandin E1
- 1 October 1972
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Ophthalmology (1950)
- Vol. 88 (4) , 418-420
- https://doi.org/10.1001/archopht.1972.01000030420013
Abstract
Intravenous infusion of prostaglandin E1 (PGE,) (0.79μg/7.9μI/min) increased intraocular pressure and lowered mean femoral arterial blood pressure in rabbits. These two effects occurred within 20 seconds after the onset of infusion and continued during the ten-minute infusion period. No significant change in outflow facility was found during the PGE, infusion. Topical pretreatment with epinephrine solution (0.5%, 1%, and 2%) antagonized the ocular hypertension produced by intravenous infusion of PGE1.Keywords
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