Antigenic analysis ofHaemophilus ducreyiby Western blotting

Abstract
SUMMARY: Twenty-one strains ofHaemophilus ducreyiwere analysed by Western blotting using two antisera produced in mice. Common antigens of molecular weights 58, 46, 41, 28, 22 and 16 kDa were detected in all the strains. The antigens were protein in nature, since they could not be detected in whole-cell lysates which had been treated with proteinase K. TheH. ducreyistrains showed antigenic cross-reactivity with strains ofH. influenzaeandH. parainfluenzae, but showed minimal or no cross-reactivity with seven other species of bacteria.
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