Preparative Enzymatic Conversion of Guanosine-5′ -monophosphate to Guanosine-5′ - triphosphate
- 1 January 1990
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1990 (11) , 709-710
- https://doi.org/10.1055/s-1990-21221
Abstract
An enzyme reactor containing guanylate kinase (EC 2.7.4.8) and pyruvate kinase (EC 2.7.1.40) was used for the preparative synthesis of guanosine-5′ -triphosphate (GTP) starting from guanosine-5′ -monophosphate (GMP), phospho(enol)-pyruvate (PEP) [2-(phosphonooxy)-2-propenoic acid] and catalytic amounts of adenosine-5′ -triphosphate (ATP).Keywords
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