INFLUENCE OF ANTIBODIES AND THERMOLABILE SERUM FACTORS ON THE BACTERICIDAL ACTIVITY OF HUMAN NEUTROPHIL GRANULOCYTES
- 1 November 1976
- journal article
- research article
- Published by Wiley in Acta Pathologica Microbiologica Scandinavica Section C Immunology
- Vol. 84C (2) , 112-118
- https://doi.org/10.1111/j.1699-0463.1976.tb00007.x
Abstract
The influence of serum antibodies and thermolabile serum factors on the intracellular killing of Staphylococcus aureus by neutrophil granulocytes has been examined using a method which facilitates a precise in vitro evaluation of the phagocytic and bactericidal activities of human polymorphonuclear leucocytes. The bactericidal activity of the granulocytes was significantly less pronounced in the presence of serum absorbed with Staph. aureus or inactivated at 56°C for 30 minutes than in the presence of untreated serum. Specific antibodies seemed to stimulate the intracellular killing of bacteria more than thermolabile serum factors.Keywords
This publication has 9 references indexed in Scilit:
- INFLUENCE OF SERUM ON THE BACTERICIDAL ACTIVITY OF NEUTROPHIL GRANULOCYTESActa Pathologica Microbiologica Scandinavica Section B Microbiology and Immunology, 2009
- Evaluation of Neutrophil Granulocyte FunctionsActa Pathologica Microbiologica Scandinavica Section B Microbiology and Immunology, 2009
- NEUTROPHIL GRANULOCYTE FUNCTION IN BACTERIAL INFECTIONSThe Lancet, 1972
- Disorders of Phagocyte FunctionCurrent Problems in Pediatrics, 1972
- Evaluation of Phagocytic Activity by Ingestion of Labeled BacteriaThe Journal of Infectious Diseases, 1971
- Receptors for human γG Globulin on human neutrophilsJournal of Clinical Investigation, 1970
- PHAGOCYTOSIS IN SUBACUTE BACTERIAL ENDOCARDITISThe Journal of Experimental Medicine, 1968
- Neutrophil and Eosinophil LeucocytesPublished by Elsevier ,1965