Mepyramine, a Histamine H1 Receptor Inverse Agonist, Binds Preferentially to a G Protein-coupled Form of the Receptor and Sequesters G Protein
Open Access
- 1 August 2004
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 279 (33) , 34431-34439
- https://doi.org/10.1074/jbc.m400738200
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Emerging safety issues regarding long-term usage of H1-receptor antagonistsExpert Opinion on Drug Safety, 2002
- Inverse agonism: pharmacological curiosity or potential therapeutic strategy?Published by Elsevier ,2000
- Human adenosine A1 receptor and P2Y2‐purinoceptor‐mediated activation of the mitogen‐activated protein kinase cascade in transfected CHO cellsBritish Journal of Pharmacology, 1998
- Studies on the Novel Antiallergic Agent HSR-609: Its Penetration into the Central Nervous System in Mice and Guinea Pigs and Its Selectivity for the Histamine H1ReceptorThe Japanese Journal of Pharmacology, 1997
- The Cubic Ternary Complex Receptor-Occupancy Model III. Resurrecting EfficacyJournal of Theoretical Biology, 1996
- The Cubic Ternary Complex Receptor–Occupancy Model II. Understanding Apparent AffinityJournal of Theoretical Biology, 1996
- The Cubic Ternary Complex Receptor–Occupancy Model I. Model DescriptionJournal of Theoretical Biology, 1996
- The two-state model of receptor activationTrends in Pharmacological Sciences, 1995
- Agonist-antagonist interactions at angiotensin receptors: application of a two-state receptor modelTrends in Pharmacological Sciences, 1994
- Heterogeneity of [3H]-mepyramine binding sites in guinea pig cerebellum and lungInflammation Research, 1991