Absence of mutations in the β‐catenin and adenomatous polyposis coli genes in papillary and follicular thyroid carcinomas
- 1 September 2001
- journal article
- research article
- Published by Wiley in Pathology International
- Vol. 51 (9) , 680-685
- https://doi.org/10.1046/j.1440-1827.2001.01269.x
Abstract
β‐Catenin has multiple functions both in intercellular adhesion and in signal transduction. As a signaling molecule, mutations in exon 3 of the β‐catenin gene stabilize this protein in the cytoplasm...Keywords
This publication has 35 references indexed in Scilit:
- Nuclear Accumulation of Mutated β-Catenin in Hepatocellular Carcinoma Is Associated with Increased Cell ProliferationThe American Journal of Pathology, 1999
- A common human skin tumour is caused by activating mutations in β-cateninNature Genetics, 1999
- β-Catenin regulates expression of cyclin D1 in colon carcinoma cellsNature, 1999
- Mutations of the β‐Catenin Gene in Endometrial CarcinomasJapanese Journal of Cancer Research, 1999
- Identification of c- MYC as a Target of the APC PathwayScience, 1998
- Somatic mutations of the β-catenin gene are frequent in mouse and human hepatocellular carcinomasProceedings of the National Academy of Sciences, 1998
- Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta -catenin and promotes GSK-3beta -dependent phosphorylation of beta -cateninThe EMBO Journal, 1998
- β-catenin is a target for the ubiquitin–proteasome pathwayThe EMBO Journal, 1997
- Signal transduction by β-cateninCurrent Opinion in Cell Biology, 1995
- A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinomaNature, 1994