Anti-heart Serum and Reactivity of Different Cell Types in Tissue Culture.

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Abstract
Further evidence for species specificity and for lack of organ or cell type specificity of an antiserum to chick embryo heart cells has been obtained from tissue culture studies. Fibroblasts from chick embryo spleen, liver, and heart react. Epithelial cells from intestine react. Mouse fibroblasts and malignant human epithelial cells showed no reaction. Passive sensitization of cells in tissue culture could not be adequately demonstrated and attempts to test the reactivity of endothelium or smooth muscle were unsuccessful.