F-prime factor formation inE. coliK12
- 1 September 1966
- journal article
- research article
- Published by Hindawi Limited in Genetics Research
- Vol. 8 (2) , 189-196
- https://doi.org/10.1017/s0016672300010041
Abstract
A model for F-prime formation is presented. It predicts that an Hfr strain giving rise to an F-prime factor would acquire a deletion corresponding to the chromosomal fragment carried by the episome. Genetic studies have confirmed this prediction. Concomitant transfer to the episome of a gene determining a function vital to the cell has permitted selection of derived Hfr strains in which the episomal fragment has been translocated to various sites on the bacterial chromosome.This publication has 12 references indexed in Scilit:
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