HYPERVITAMINOSIS A AND THE DISTRIBUTION OF BODY IODINE
- 1 August 1948
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 43 (2) , 120-123
- https://doi.org/10.1210/endo-43-2-120
Abstract
50 adult male albino rats were divided into 3 groups. Two exptl. series received daily doses of 15,000 and 20,000 I.U. of vitamin A orally for 14 and 18 days, respectively. Hypervitaminosis A was accompanied by a decrease in protein-bound iodine in the liver and thyroid, and by an increase in protein-bound iodine in serum, pituitary and skeletal muscle. The authors suggest these results are due to a decreased hepatic destruction of thyroxine with consequent hyperthyroxinemia.Keywords
This publication has 7 references indexed in Scilit:
- EFFECTS OF VITAMIN A DEFICIENCY ON THYROID FUNCTION STUDIED WITH RADIOACTIVE IODINE1,2Endocrinology, 1947
- USE OF MASSIVE DOSES OF VITAMIN A IN THE TREATMENT OF HYPERTHYROIDISMJournal of Clinical Endocrinology & Metabolism, 1947
- IODINE IN BLOOD AND THYROID OF MAN AND SMALL ANIMALSEndocrinology, 1944
- INTERRELATIONS BETWEEN THYROID FUNCTION AND VITAMIN METABOLISMPhysiological Reviews, 1943
- The Effect of Vitamins A and C on Experimental HyperthyroidismJournal of Nutrition, 1940
- The Effects of a Deficiency of Iodine and Vitamin A on the Thyroid Gland of the Albino RatJournal of Nutrition, 1935
- EFFECTS OF COD-LIVER OIL ON BASAL METABOLISM AND ON THE THYROID LANDEndocrinology, 1934