Abstract
Studies of five smokers and five nonsmokers gave supporting evidence that smokers, in comparison to nonsmokers, have low vitamin C plasma and blood levels and retain more ascorbic acid from load tests. During a desaturation period of 13 days on a vitamin C-deficient diet, the rate of loss of vitamin C in blood and plasma was about the same in both groups and there was no significant difference in retention by a resaturation test.

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