EFFECT OF INJECTED VOLUME AND SPEED OF INJECTION ON THE SPREAD OF SPINAL ANAESTHESIA WITH ISOBARIC AMETHOCAINE

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Abstract
Amethocaine 10 mg in isobaric solution was injected intrathecally in 40 patients. Three volumes (1, 2 and 4 ml) of injection and two rates of injection (1 ml per 5 s and 1 ml per 10 s) were studied. Small volumes (1 and 2 ml) of the more concentrated solutions (1 % and 0.5%) produced predictable blockade with spread restricted to the lower thoracic segments. Increasing the volume had little effect on the mean height of spinal blockade, but blockade was less predictable. Slowing the speed of injection of the largest volume (4 ml) partly counteracted this effect.

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