Methotrimeprazine in the Treatment of Labor Pain

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Abstract
METHOTRIMEPRAZINE, an interesting analgesic agent1 is, chemically, a phenothiazine and thus unrelated to the known potent analgesics. It also seems devoid of addiction liability in monkey2 and man3 and is less of a respiratory depressant, in equianalgesic doses, than morphine.4 The present study was undertaken to investigate the analgesic performance and side-action liability of this drug in a situation quite different from postoperative pain,1 comparing it with a standard narcotic analgesic (meperidine) and with a placebo. The results indicate a general similarity in the activity of meperidine and methotrimeprazine, with both compounds differing significantly from the placebo. The experimental design . . .

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