CLINICAL STUDIES OF INDUCTION AGENTS IV: A COMPARISON OF G.29.505 AND THIOPENTONE AS MAIN ANAESTHETIC AGENTS FOR A STANDARD OPERATION

Open Access
Publisher Website
Google Scholar
Abstract
Thiopentone and a non-barbiturate, G.29.505, were compared as main anaesthetic agents combined with nitrous oxide and oxygen for the operation of dilatation and curettage with atropine as sole premedication. Muscle movement following injection occurred more frequently with G.29.505 but thiopentone caused more hypotension. The respiratory depression sometimes seen with the barbiturate was replaced by transient hyperventilation when G.29.505 was used. Using a system for “grading” the course of anaesthesia it was found that both drugs were equally satisfactory. Complete return of consciousness occurred more quickly with the non-barbiturate, but the latter caused a much higher incidence of vomiting and nausea during the first hour after operation.

This publication has 0 references indexed in Scilit: