Effect of Bleeding on Rabbit Marrow Polyunsaturated Fatty Acids

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Abstract
Marrow fats of 12 experimental anemic rabbits were analyzed spectrophotometrically. Of these, 6 were anemic from simple bleeding and 6 from bleeding followed by intraperitoneal rein-jection of laked red corpuscles. When the hemopoietic mechanism is under stress of anemia, the percentage as well as absolute quantities of linoleic and linolenic acids decrease, but loss of these acids is not related to hemoglobin synthesis. Marrow fat is predominantly a storage depot for body energy, but with the auxiliary function of contributing some of its substance to the blood cells. In experimental anemia linoleic and linolenic acids are preferentially transported from marrow, principally by the blood plasma.

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