VARIATION OF THE CONFORMATION OF THE ACTIVE SITE OF α-CHYMOTRYPSIN WITH HYDROGEN ION CONCENTRATION
- 1 November 1963
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 50 (5) , 817-821
- https://doi.org/10.1073/pnas.50.5.817
Abstract
It has been shown that the nature of modification (inhibition or activation) processes encountered in a -chymotrypsin-catalyzed reactions is dependent upon the hydrogen ion concentration of the reaction system. This observation has been interpreted in terms of variation of the conformation of the active site of the enzyme with hydrogen ion concentration.This publication has 2 references indexed in Scilit:
- The calculation of kinetic constants of enzyme-catalyzed reactions using digital computersBiochimica et Biophysica Acta, 1960
- The association of α-chymotrypsin and its influence upon the kinetics of a reaction catalyzed by this enzymeBiochimica et Biophysica Acta, 1957