Cysteine-Derived Organocatalyst in a Highly Enantioselective Intramolecular Michael Reaction
- 26 October 2005
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 127 (46) , 16028-16029
- https://doi.org/10.1021/ja055740s
Abstract
Asymmetric intramolecular Michael reaction catalyzed by an organocatalyst derived from cysteine has been developed for the synthesis of chiral bicyclo[4.3.0]nonene and cis-disubstituted cyclopentane skeletons with a creation of three or two contiguous chiral centers in good yield with high diastereo- and excellent enantioselectivities.Keywords
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