The Effect of Antithrombin III on the Activity of the Coagulation Factors VII, IX and X
- 1 January 1976
- journal article
- research article
- Published by Georg Thieme Verlag KG in Thrombosis and Haemostasis
- Vol. 35 (02) , 295-304
- https://doi.org/10.1055/s-0038-1647922
Abstract
Antithrombin III, purified to homogeneity according to Polyacrylamide gel disc electrophoresis and immunoelectrophoresis, inhibited the activity of purified factor IXa and Xa, whereas factor VII was not inhibited either in the active or in the native form. Antithrombin III is the single most important inhibitor of factor Xa in plasma. Factor Xa does not, however, reduce the activity of antithrombin III against thrombin.This publication has 8 references indexed in Scilit:
- α2-Macroglobulin as Progressive AntithrombinNature, 1967
- Purification of Two Progressive Antithrombins of Human PlasmaScandinavian Journal of Clinical and Laboratory Investigation, 1967
- Inhibition of the Thrombin-fibrinogen Reaction by Antithrombin III, Studied by N-terminal AnalysisScandinavian Journal of Clinical and Laboratory Investigation, 1967
- Studies on tissue thromboplastinBiochimica et Biophysica Acta (BBA) - General Subjects, 1966
- Isoelectric Fractionation, Analysis, and Characterization of Ampholytes in Natural pH Gradients. IV. Further Studies on the Resolving Power in Connection with Separation of Myoglobins.Acta Chemica Scandinavica, 1966
- DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS*Annals of the New York Academy of Sciences, 1964
- Studies on proconvertin (factor vii) iv. The adsorption on barium sulphateScandinavian Journal of Clinical and Laboratory Investigation, 1964
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951