Surface Properties of Lung Extracts

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Abstract
The importance of surface properties in the layer lining the alveoli is now well established. For measuring these properties a dynamic model of the alveolus has been constructed. It has the following advantages over previous techniques used to study the surface tension of biological fluids including lung extracts: It more closely simulates the physiologic changes in rate and area that occur in the lungs during respiration. Only a small volume of fluid (0.2 ml) is required. The surface tension can be determined in 30 min or less. It is suggested that the Viscoelastic properties of the alveolar surface film may be important as well as the surface tension in determining the response to compression and expansion.

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