Genetic Aspects of Salivary Secretion of Isoagglutinins.

Publisher Website
Google Scholar
Abstract
Summary Whole saliva was collected from 201 individuals, a number of which were selected specifically for mating studies. Blood types and ability to secrete salivary isoagglutinins were determined. Salivary isoag-glutinins were detected in 31% of blood type A individuals, 46.2% of type B and 75% of type O. The following observations suggest that the ability to secrete salivary isoagglu-tinin is genetically influenced. 1. Blood type O individuals were able to secrete anti-A without secreting anti-B isoagglutinin, or the converse. 2. A comparison of salivary and serum isoagglutinin shows that the serum ti-ters are generally reflected by salivary titers in secretors; serum levels alone, however, do not account for the secretion of salivary iso-agglutinins. 3. Twenty-two matings suggest that the ability to secrete isoagglutinin by type A humans (anti-B) is a recessive characteristic and the secretor ability in type O is not sex-linked. The term “iso-secretor” is suggested for humans who secrete isoaggluti-nins to avoid confusion with the term “secretor” used to describe those who secrete the A B O blood group antigens.

This publication has 1 reference indexed in Scilit: