Differential Effects of Oral and Transdermal Estrogen/Progesterone Regimens on Sensitivity to Activated Protein C Among Postmenopausal Women
- 1 September 2003
- journal article
- clinical trial
- Published by Wolters Kluwer Health in Arteriosclerosis, Thrombosis, and Vascular Biology
- Vol. 23 (9) , 1671-1676
- https://doi.org/10.1161/01.atv.0000087141.05044.1f
Abstract
Objective— Activated protein C (APC) resistance not related to the factor V Leiden mutation is a risk factor for venous thrombosis. Oral estrogen replacement therapy (ERT) has been reported to indu...Keywords
This publication has 28 references indexed in Scilit:
- Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled TrialJAMA, 2002
- Hormone replacement therapy in healthy postmenopausal women: a randomized, placebo-controlled study of effects on coagulation and fibrinolytic factorsJournal of Internal Medicine, 2001
- The Effects of Hormone Replacement Therapy on Hemostatic Variables in Women with Angiographically Verified Coronary Artery Disease: Results from the Estrogen in Women with Atherosclerosis StudyThrombosis Research, 2000
- Acquired APC resistance and oral contraceptives: differences between two functional testsBritish Journal of Haematology, 1999
- The effects of oestrogen replacement therapy on haemostatic variables in postmenopausal women with non-insulin-dependent diabetes mellitusBlood Coagulation & Fibrinolysis, 1999
- Effect of activated protein C on thrombin generation and on the thrombin potential in plasma of normal and APC-resistant individualsBlood Coagulation & Fibrinolysis, 1997
- Risk of hospital admission for idiopathic venous thromboembolism among users of postmenopausal oestrogensThe Lancet, 1996
- Risk of venous thromboembolism in users of hormone replacement therapyThe Lancet, 1996
- Prospective study of exogenous hormones and risk of pulmonary embolism in womenThe Lancet, 1996
- Mutation in blood coagulation factor V associated with resistance to activated protein CNature, 1994