The use of an immobilized aldolase in the first synthesis of a natural deaminated neuraminic acid

1 January 1987

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications

No. 11,p. 859-860
https://doi.org/10.1039/c39870000859

Abstract

The first synthesis of 3-deoxy-D-glycero-D-galacto-nonulosonic acid (KDN)(1) was achieved by condensation of the non-nitrogeneous substrate D-mannose (2) with pyruvate, catalysed by immobilized acylneuraminate pyruvate lyase.

Keywords

NITROGENEOUS
ALDOLASE
IMMOBILIZED
GLYCERO
ACYLNEURAMINATE
NONULOSONIC
CONDENSATION
GALACTO
MANNOSE
DEAMINATED

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