Ultrasound Examination of Skin Thickness in Patients with Progressive Systemic Sclerosis (Scleroderma)
- 1 January 1986
- journal article
- research article
- Published by SAGE Publications in Acta Radiologica. Diagnosis
- Vol. 27 (1) , 91-94
- https://doi.org/10.1177/028418518602700117
Abstract
A new ultrasound technique for measuring skin thickness in 40 patients with progressive systemic sclerosis (scleroderma) and in 10 healthy control subjects has been evaluated. High frequency (10 MHz) dynamic ultrasound examination was performed at the proximal and middle phalanges of both second fingers. Measurements of the control subjects on two separate occasions demonstrated a good reproducibility of the technique with a standard deviation of 0.06 mm. The skin was thicker in patients with scleroderma 3.3±0.7 mm (mean ± SD) compared with control subjects 2.5±0.2 mm (p<0.001). No relation between skin thickness and duration of disease was observed. This method can be used to monitor changes in skin thickness over time.This publication has 5 references indexed in Scilit:
- Progressive Systemic SclerosisClinics in Rheumatic Diseases, 1983
- D-Penicillamine Therapy in Progressive Systemic Sclerosis (Scleroderma)Annals of Internal Medicine, 1982
- Preliminary criteria for the classification of systemic sclerosis (scleroderma)Arthritis & Rheumatism, 1980
- Progressive Systemic Sclerosis: Clinical Features and Pathogenesis of Cutaneous Involvement (Scleroderma)Clinics in Rheumatic Diseases, 1979
- Skin thickness and collagen content in progressive systemic sclerosis and localized sclerodermaArthritis & Rheumatism, 1979