Reactions of the Trichloromethylperoxy Free Radical (Cl3COO.) with Tryptophan, Tryptophanyl-tyrosine and Lysozyme
- 1 January 1981
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology
- Vol. 39 (2) , 135-141
- https://doi.org/10.1080/09553008114550151
Abstract
The trichloromethyl peroxy radical Cl3COO. reacts with tryptophan, tryptophanyl-tyrosine and with lysozyme to form products whose overall absorption spectrum is different from those observed following the reaction of hydroxyl, bromide, thiocyanate or azide radicals. Two spectral components have been identified: a minor component attributed to the neutral tryptophanyl radical which can react with ascorbate and intramolecularly with tyrosine residues and a major component which does not undergo either of these reactions and is probably a radical adduct.This publication has 10 references indexed in Scilit:
- Electron transfer reactions of halogenated aliphatic peroxyl radicals: measurement of absolute rate constants by pulse radiolysisJournal of the Chemical Society, Perkin Transactions 2, 1980
- Reactions of the carbon tetrachloride-related peroxy free radical (CCl3O2.) with amino acids : Pulse radiolysis evidenceLife Sciences, 1978
- Mechanism of tryptophan oxidation by some inorganic radical-anions: a pulse radiolysis studyJournal of the Chemical Society, Faraday Transactions 1: Physical Chemistry in Condensed Phases, 1976
- Free-Radical Chain Oxidation by Carbon Tetrachloride and Related Compounds: Model Pulse-Radiolysis StudiesBiochemical Society Transactions, 1973
- Die Reduktion von Tetrachlorkohlenstoff durch hydratisierte Elektronen, Η-Atome und reduzierende Radikale / The Reduction of Carbon Tetrachloride by Hydrated Electrons, H-Atoms, and Reducing RadicalsZeitschrift für Naturforschung B, 1971
- Absorption spectrum and decay rate of the ascorbic acid radicalJournal of the American Chemical Society, 1970
- Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 Å ResolutionNature, 1965