Intracranial Venous Thrombosis During the First Trimester of Pregnancy

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Abstract
Two patients are reported who developed a spontaneous thrombosis of the superior longitudinal sinus during the first trimester of pregnancy. The clinical picture associated with this lesion was characterized by the acute onset of an organic mental syndrome, followed by generalized convulsions, progressive stupor, and death from respiratory arrest within a few days of the onset. At necropsy there was hemorrhagic infarction of the cerebral cortex, secondary to aseptic thrombosis of the superior longitudinal sinus. No cause for the thrombus formation could be determined.

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