PfamAlyzer: domain-centric homology search
Open Access
- 31 October 2007
- journal article
- research article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 23 (24) , 3382-3383
- https://doi.org/10.1093/bioinformatics/btm521
Abstract
Summary: PfamAlyzer is a Java applet that enables exploration of Pfam domain architectures using a user-friendly graphical interface. It can search the UniProt protein database for a domain pattern. Domain patterns similar to the query are presented graphically by PfamAlyzer either in a ranked list or pinned to the tree of life. Such domain-centric homology search can assist identification of distant homologs with shared domain architecture. Availability: PfamAlyzer has been integrated with the Pfam database and can be accessed at http://pfam.cgb.ki.se/pfamalyzer. Contact:Erik.Sonnhammer@ki.seKeywords
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