Polyurethane Enzyme Membranes for Chip Biosensors
- 1 August 1989
- journal article
- research article
- Published by Taylor & Francis in Analytical Letters
- Vol. 22 (9) , 2175-2190
- https://doi.org/10.1080/00032718908051246
Abstract
The coverage of electrochemical chip sensors based on silicon technology with a polyurethane enzyme membrane is described. After crosslinking of the surface by polyfunctional isocyanates the enzyme membrane shows good adhesion, complete retention of the enzyme molecules, and low diffusional resistance to both analytes and products. Using thin film noble metal electrodes and ion sensitive field effect transistors, glucose and urea sensors with good long term stability and short response time have been prepared.Keywords
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