Hybridization of Alternating Cationic/Anionic Oligonucleotides to RNA Segments
- 1 July 1994
- journal article
- research article
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 13 (6-7) , 1597-1605
- https://doi.org/10.1080/15257779408012174
Abstract
It is shown that oligonucleotide analogues containing alternating phosphodiester groups and cationic groups linked to phosphorus through an amidate bond hybridize to complementary RNA segments. An improved synthetic procedure for the alternating compounds is also described.Keywords
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